Authors: Pinto, L.S.; De Souza. M.V.N.
Source: Synthesis-Stuttgart, v. 49, p. 2677-2682, 2017.
Publisher: Georg Thieme Verlag Stuttgart · New York
This study describes a general procedure for the synthesis of different coumarins via sonochemistry using active methylene compounds and 2-hydroxybenzaldehydes or resorcinol. The application of sonochemistry for the synthesis of these compounds was also very effective on a multigram scale with a higher yield, higher amount of crystalline compound, and shorter reaction time compared with the compounds obtained using the classical procedures.
Keywords: coumarins – sonochemistry – synthesis – multigram scale – smaller scale
Publication date: 1 de Março de 2017